The Nuphedragen Review

Dicaffeine Malate, an ionic compound of caffeine and Malic acid, is extensively used in soft-drinks and energy drinks. It is a mild alternative to caffeine and is gentle on the digestion. It perks energy levels and boosts thermogenesis. Caffeine is known to be a stimulant as well as a solution for weight loss. The Dicaffeine Malate combination is a good substitute for natural caffeine, since it not only augments its benefits but also eases a few of its side effects. Dieters who experience nausea, jitters, insomnia and high blood pressure due to natural caffeiene intake should switch to Dicaffeine Malate weight loss supplements. Malic acid provides energy boost by converting fats, proteins and carbs into water and CO2. Thus, the use of Dicaffeine Malate in fat loss supplements aids metabolic activity.

Methylxanthines (Caffeine) is basically a type of bronchodilator, methylxanthine is considered highly effective in the treatment of COPD. Due to its ability to relax the airways, it enables the patient to breathe more easily. For the same reason, it is believed to improve respiratory muscle strength when administered orally or intravenously. Caffeine, a widely used psychoactive substance, belongs to this group of compounds called as methylxanthines. Caffeine gives rise to number of neurological side effects such as anxiety, insomnia, restlessness, and tachycardia. On the other hand, low to moderate consumption of caffeine can lead to positive effects such as enhanced alertness, energy and better concentration. Some people may experience withdrawal symptoms after about 12 to 24 hours after sudden cessation of caffeine consumption while some individuals may report of such symptoms within 3 to 6 hours.

PEA (Phenylethylamine) is a monoamine and alkaloid which functions as a trace amine, neurotransmitter or a neuromodulator. Phenylalanine, an amino acid, is the source from which phenethylamine, another name for PEA, is naturally biosynthesized through enzymatic decarboxylation. Compounds that are found in supplements in form of phenethylamines can be very diverse and include entactogens, anorectics, bronchodilators, hallucinogens, antidepressants and stimulants. Substituted phenethylamines are related to amphetamines, but also to dopamine, epinephrine, norepinephrine, phenylalanine and tyrosine. PEA is used by body builders and sportspeople mainly because of the stimulative effects as a neuromodulator, raising alertness, mood, concentration and focus. The additional stimulation of AMPA receptors, which boosts release of acetylcholine through the glutamatergic system, is an additional bonus of this popular supplement ingredient.

Synephrine HCL, also known as oxedrine, is a drug designed primarily to encourage fat loss. This is achieved by stimulating the beta-3 receptors. Doing so increases the metabolic rate leading to fat loss. Synephrine is a stimulant similar to caffeine and ephedrine and it is believed to provide an energy boost, suppress appetite and increase metabolism. The combination of all leads to burning more calories. Studies have stated that synephrine stimulates fat metabolism without the usual negative cardiovascular side effects. The effectiveness of synephrine is increased by combining it with HCL. This allows for increased absorption and more solubility in water. However regardless of the increasing popularity of synephrine HCL, there are still some debates over its over all effects and it being used as an alternative to ephedrine, a substance made illegal by many countries due to the side effects including heart disease.